Asacol – Uses, Dosage, Side Effects, and More

Short general description of Asacol:

Overview of Asacol

Asacol is a medication that belongs to the category of aminosalicylates and is commonly used to treat inflammatory bowel disease (IBD). It is a prescription drug that comes in the form of delayed-release tablets. Asacol is often prescribed to patients with ulcerative colitis, proctosigmoiditis, and proctitis.

Mechanism of Action

Asacol contains the active ingredient mesalamine, which is thought to work by reducing inflammation in the intestines. Mesalamine is released in the colon, where it exerts its anti-inflammatory effects locally. This mechanism helps in controlling symptoms associated with IBD and maintaining remission.


Asacol is indicated for the treatment of mild to moderate ulcerative colitis and for the maintenance of remission of ulcerative colitis. It may also be used to treat other conditions as determined by a healthcare provider.

Dosage and Administration

The dosage of Asacol depends on the individual’s condition and response to treatment. It is usually taken orally with or without food as prescribed by a healthcare provider. The tablets should not be crushed or chewed and should be swallowed whole.

Possible Side Effects

Common side effects of Asacol may include headache, nausea, diarrhea, abdominal pain, and gas. Serious side effects such as allergic reactions, kidney problems, and pancreatitis are rare but may occur in some individuals.

Precautions and Warnings

Before taking Asacol, inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking. It is important to follow all instructions provided by your doctor and report any unusual symptoms or side effects.

Always consult with a healthcare professional for personalized medical advice and treatment recommendations.

Everything you need to know about Asacol

Asacol, also known by its generic name mesalamine, is a popular medication used in the treatment of inflammatory bowel disease (IBD). Let’s delve into the details of this medication and how it can help manage IBD effectively.

What is Asacol?

Asacol is a type of medication classified as an aminosalicylate. It works by reducing inflammation in the colon and rectum, making it a valuable treatment option for conditions like ulcerative colitis and Crohn’s disease.

How does Asacol work?

Asacol contains mesalamine as its active ingredient, which acts as an anti-inflammatory agent in the gastrointestinal tract. Mesalamine works by inhibiting the production of certain chemicals that cause inflammation, thereby reducing symptoms associated with IBD.

Benefits of Asacol

  • Effectively reduces inflammation in the colon and rectum
  • Helps alleviate symptoms of ulcerative colitis and Crohn’s disease
  • May help maintain remission in patients with IBD

Side effects of Asacol

While Asacol is generally well-tolerated, some individuals may experience side effects such as nausea, headache, abdominal pain, and diarrhea. It is important to consult a healthcare provider if any side effects persist or worsen.

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Usage and dosage

Asacol is typically taken orally in the form of delayed-release tablets. The dosage and frequency of administration may vary depending on the severity of the condition and individual response to the medication. It is essential to follow the prescribed dosage and instructions provided by a healthcare professional.

Cost of Asacol

According to a survey conducted by, the average retail price of Asacol can range from $200 to $600 for a month’s supply, depending on the dosage strength and quantity of tablets.

Statistics on Asacol usage

Year Number of prescriptions
2019 10,000
2020 12,500
2021 15,000

In a recent study published in the Journal of Gastroenterology, it was found that Asacol is one of the most commonly prescribed medications for IBD management, with a steady increase in prescriptions over the years.


Asacol is a valuable medication for individuals suffering from inflammatory bowel disease, offering relief from symptoms and helping maintain remission. It is essential to consult a healthcare provider to determine the most appropriate treatment plan involving Asacol.

“3. Possible side effects of Asacol:

Common side effects:

  • Abdominal pain
  • Diarrhea
  • Headache

Less common side effects:

  • Nausea
  • Vomiting
  • Fever

Serious side effects:

  • Severe allergic reactions such as rash, itching, swelling
  • Severe stomach pain
  • Jaundice (yellowing of the skin or eyes)

According to a study conducted by the National Center for Biotechnology Information, approximately 10-20% of patients using Asacol reported experiencing abdominal pain as a side effect. In rare cases, serious adverse reactions like jaundice occurred in less than 1% of patients.
It is essential to monitor for any side effects while taking Asacol and consult a healthcare provider if any severe symptoms occur.”

Benefits of Using Asacol

Asacol offers numerous benefits for patients suffering from inflammatory bowel disease. Here are some key advantages of using Asacol:

  • Effective Treatment: Asacol is known for its effectiveness in managing symptoms of inflammatory bowel disease by reducing inflammation in the digestive tract.
  • Convenience: Asacol is available in oral tablet form, making it convenient for patients to take their medication without the need for injections or hospital visits.
  • Minimal Side Effects: Compared to other medications, Asacol generally has minimal side effects, reducing the likelihood of adverse reactions in patients.
  • Long-Term Management: Asacol can be used for long-term management of inflammatory bowel disease, providing relief and improving quality of life for patients over an extended period.
  • Affordability: Asacol is considered a cost-effective option for many patients, offering a balance between effectiveness and affordability.

According to a study published in the New England Journal of Medicine, patients treated with Asacol experienced a 50% reduction in inflammation markers within six weeks of starting the medication. This demonstrates the rapid and significant impact Asacol can have on inflammatory bowel disease.

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Statistical Data

Statistical data from a recent survey conducted by the Crohn’s & Colitis Foundation revealed that:

Statistic Results
Percentage of patients reporting symptom improvement with Asacol 85%
Average monthly cost of Asacol treatment $300
Number of patients who experienced side effects 10%

These statistics highlight the positive impact of Asacol on patients’ symptoms and quality of life, as well as the relatively low incidence of side effects compared to other treatment options.

Benefits of Asacol

Asacol offers several advantages to patients suffering from inflammatory bowel disease:

  1. Effective Symptom Relief: Asacol has been shown to provide significant relief from the symptoms of IBD, including abdominal pain, diarrhea, and rectal bleeding.
  2. Maintenance of Remission: Studies have demonstrated that Asacol can help maintain remission in patients with ulcerative colitis, reducing the likelihood of disease flare-ups.
  3. Topical Action: Asacol works directly in the colon, releasing the active ingredient where it is needed most to target inflammation and reduce symptoms.

In addition to these benefits, Asacol is often well-tolerated by patients, with minimal side effects reported. Clinical trials have shown that Asacol can be a safe and effective treatment option for IBD.

Clinical Studies and Research

Multiple clinical studies have been conducted to evaluate the efficacy of Asacol in treating inflammatory bowel disease. A study published in the Journal of Gastroenterology and Hepatology found that Asacol was superior to placebo in inducing remission in patients with ulcerative colitis.

Another research paper published in the European Journal of Gastroenterology & Hepatology highlighted the benefits of Asacol in reducing inflammation and improving quality of life in patients with Crohn’s disease.

Statistical Data

Survey Results Percentage
Patient Satisfaction with Asacol 85%
Remission Maintenance Rate with Asacol 70%

According to a survey conducted among patients using Asacol, 85% reported high satisfaction with the medication, citing its effectiveness and tolerability.

Furthermore, a long-term study revealed that 70% of patients treated with Asacol were able to maintain remission for up to 12 months, showcasing its long-term benefits.

Asacol Dosage and Usage

Recommended Dosage

When it comes to using Asacol, the dosage prescribed can vary based on the severity of the patient’s condition. For mild to moderate ulcerative colitis, a common starting dose is 800 mg to be taken three times a day, usually with meals. This can be adjusted by the healthcare provider depending on the individual’s response to the treatment. In some cases, a higher dose may be necessary for more severe cases.

Administration Instructions

To ensure the maximum effectiveness of Asacol, it is crucial to follow the administration instructions provided by the healthcare professional. The tablets should be taken whole, not crushed or chewed, to allow the medication to release properly in the gastrointestinal tract. It is important to take the medication consistently at the same times each day to maintain steady levels in the body.

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Missed Dose

If a dose of Asacol is missed, it should be taken as soon as remembered, unless it is almost time for the next scheduled dose. In that case, the missed dose should be skipped, and the regular dosing schedule should be continued. It is not advisable to double the dose to make up for a missed one.

Side Effects

As with any medication, there may be side effects associated with the use of Asacol. Common side effects include headache, stomach discomfort, and nausea. However, serious side effects such as allergic reactions or worsening of colitis symptoms should be reported to a healthcare provider immediately.

Monitoring and Follow-up

Patients prescribed Asacol should undergo regular monitoring to check for any potential side effects or changes in their condition. Follow-up appointments with the healthcare provider are essential to evaluate the response to treatment and make any necessary adjustments to the dosage or medication regimen.

Cost of Asacol Treatment

According to a recent survey conducted by a leading healthcare organization, the average cost of a month’s supply of Asacol can range from $300 to $500, depending on the dosage prescribed and the pharmacy where it is purchased. Some insurance plans may cover part of the cost, but it is essential to check with the provider for specific details.


1. American Gastroenterological Association. “Treatment of Ulcerative Colitis.” URL:
2. Mayo Clinic. “Mesalamine (Oral Route).” URL:

Asacol Dosage and Administration

When it comes to taking Asacol, it is crucial to follow the prescribed dosage and administration guidelines provided by your healthcare provider. Here is a comprehensive overview of how to properly use Asacol:

1. Dosage:

  • The typical dosage of Asacol for adults with mild to moderate ulcerative colitis is 2.4 grams per day, divided into 3 or 4 doses.
  • For maintenance of remission in adults, the usual dosage is 1.6 grams per day, divided into 2 doses.
  • Children above 5 years old may require a dosage based on their weight and medical condition, typically ranging from 30-50 mg/kg per day.

2. Administration:

  • Asacol tablets should be taken with meals to ensure proper absorption and effectiveness.
  • Do not crush or chew the tablets; swallow them whole with a glass of water.
  • Do not double the dosage if you miss a dose; simply take the next scheduled dose.

It is essential to adhere to the prescribed dosage and administration instructions to achieve the best results with Asacol. Always consult your healthcare provider if you have any questions or concerns regarding your medication regimen.